Figure 1

SSP fitting of DCE-MRI data collected from normal human heart in vivo. The points represent data collected at four times: one prior to CA administration, and three post-CA administration. R_1t is the myocardial tissue ¹H₂O R₁ value, and R_1p is the blood plasma ¹H₂O R₁ value calculated for a hematocrit (Hct) of 0.4. The solid curve represents the best SS model fitting to the data with parameters shown in the inset. The dashed asymptotic line is expected for the tracer paradigm.