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Figure 1 | Journal of Cardiovascular Magnetic Resonance

Figure 1

From: Advanced assessment of cardiac morphology and prediction of gene carriage by CMR in hypertrophic cardiomyopathy - the HCMNet/UCL collaboration

Figure 1

Evolution of cardiac trabeculae in embryonic mice analyzed via fractal analysis of high-resolution (2-3 μm) episcopic microscopy datasets in complete registration. This atlas of wild-type NIMR:Parkes mice provides the first detailed analyses of quantitative changes in the anatomical complexity of trabeculae during cardiac morphogenesis. The atlas was compiled from analyses of mice at ages: E14.5, n = 12; E15.5, n = 14; E16.5, n = 13; E17.5, n = 12 and E18.5, n = 12. Top section: Murine hearts in short axis with insert (bottom left) showing relative slice location along the LV. Scale bars in millimeters are included for E14.5 and E18.5. Bottom section: Black lines = mean fractal dimension; Coloured ribbons = 95% confidence intervals. E = embryonic day.

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