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Table 1 Age, aortic diameter and mean WSS in the AAo, arch and DAo of the cohort-specific WSS atlases.

From: Thoracic aortic wall shear stress atlases in patients with bicuspid aortic valves

 

Controls

BAV

BAV with Dilation

BAV Stenosis

Age+ (y)

50 ± 14

44 ± 10

53 ± 10

44 ± 10

SOV diameter* (cm)

3.0 ± 0.5

3.5 ± 0.4

4.0 ± 0.3

3.7 ± 0.4

MAA diameter* (cm)

2.9 ± 0.5

3.4 ± 0.4

4.4 ± 0.3

3.4 ± 0.4

Mean WSS AAo* (Pa)

0.51 ± 0.16

0.55 ± 0.24

0.71 ± 0.46

0.61 ± 0.37

Mean WSS arch* (Pa)

0.50 ± 0.14

0.63 ± 0.18

1.05 ± 0.27

0.73 ± 0.32

Mean WSS Dao* (Pa)

0.64 ± 0.10

0.64 ± 0.12

1.16 ± 0.27

0.67 ± 0.14

Comparison

BAV vs. Controls

BAV with dilation vs. Controls

BAV stenosis vs. Controls

Percentage significant difference AAo (%)**

28

41

37

Percentage significant difference arch (%)**

20

86

35

Percentage significant difference DAo (%)**

0

67

0

Median/mean angle AAo (°)*

23/32

34/46

26/43

Median/mean angle arch (°)*

9/13

14/19

15/19

Median/mean angle DAo (°)*

6/6

6/7

6/7

  1. Percentage significant difference shows the percentage of the area of the AAo, arch and DAo, where the difference with the control atlas on the shared geometry was significant. The median/mean angle represents the median and mean of the angle difference of the WSS vector with the control atlas on the shared geometry.
  2. SOV = Sinus of Valsalva, MAA = Mid-Ascending aorta, AAo = Ascending aorta, DAo = Descending aorta + Not significant across cohorts using a Kruskal-Wallis test (p = 0.3) *Significant across cohorts using a Kruskal-Wallis test (p < 0.05) ** Significance tested with a Wilcoxon rank sum test (p < 0.05)