a. RIC reduced infarct size. Patients randomized to RIC sustained a significantly smaller myocardial infarct size (% LV). Values are mean ± SEM. *P = 0.009. Figure 1b. RIC reduced extent of edema. Unexpectedly, in patients randomized to RIC the extent of myocardial edema delineated by quantitative T2-mapping (% LV) was significantly reduced. Values are mean ± SEM. *P = 0.003.