Table 1 CMR data in Healthy Controls and Patients with Severe AS pre- and post-AVR

Age (years)

60 ± 8

60 ± 11

62 ± 10

0.91

1.00

0.29

Male (%)

66.67

66.67

66.67

1.00

1.00

1.00

Systolic Blood Pressure (mmHg)

120 ± 4

123 ± 9

134 ± 12

0.001

0.56

0.0004

Diastolic Blood Pressure (mmHg)

74 ± 7

79 ± 8

76 ± 12

0.38

0.17

0.16

Heart rate (beats/min)

72 ± 12

68 ± 10

68 ± 10

0.61

0.35

0.85

BMI (kg/m2)

25 ± 6

28 ± 6

28 ± 6

0.55

0.26

0.16

Cardiac Magnetic Resonance:

LV EF (%)

64 ± 5

67 ± 7

61 ± 5

0.01

0.21

0.005

LVEDV (mls)

123 ± 21

147 ± 38

132 ± 25

0.19

0.14

0.03

LVESV (mls)

43 ± 13

49 ± 19

51 ± 13

0.72

0.65

0.6

LV mass index (g/m2)

47 ± 5

72 ± 12

60 ± 8

<0.001

<0.0001

0.0003

RVEF (%)

53.2 ± 2

58.9 ± 7.2

54.8 ± 5.7

0.063

0.07

0.005

ECV

0.28 ± 0.03

0.33 ± 0.04

0.36 ± 0.03

<0.001

0.01

<0.001

LAV max index (ml/m2)

31 ± 8

50 ± 14

34 ± 9

<0.001

0.003

0.0009

LAV bac index (ml/m2)

19 ± 7

37 ± 12

30 ± 7

<0.001

0.001

0.03

LAV min index (ml/m2)

12 ± 5

20 ± 6

17 ± 4

0.009

0.009

0.22

LAPEF (%)

40 ± 9

26 ± 8

13 ± 9

<0.001

0.003

<0.0001

LACEF (%)

39 ± 5.2

46 ± 12

41 ± 9

0.26

0.18

0.3