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Table 1 CMR data in Healthy Controls and Patients with Severe AS pre- and post-AVR

From: Left atrial passive function after aortic valve replacement in aortic stenosis

Variable Healthy Controls (N = 6)* AS Pre-AVR (N = 18)* ** AS Post-AVR (N = 18) ** P-value, ANOVA *P-value, Healthy Controls vs. AS Pre-AVR **P-value, AS Pre-AVR vs. AS Post-AVR
Age (years) 60 ± 8 60 ± 11 62 ± 10 0.91 1.00 0.29
Male (%) 66.67 66.67 66.67 1.00 1.00 1.00
Systolic Blood Pressure (mmHg) 120 ± 4 123 ± 9 134 ± 12 0.001 0.56 0.0004
Diastolic Blood Pressure (mmHg) 74 ± 7 79 ± 8 76 ± 12 0.38 0.17 0.16
Heart rate (beats/min) 72 ± 12 68 ± 10 68 ± 10 0.61 0.35 0.85
BMI (kg/m2) 25 ± 6 28 ± 6 28 ± 6 0.55 0.26 0.16
Cardiac Magnetic Resonance:       
LV EF (%) 64 ± 5 67 ± 7 61 ± 5 0.01 0.21 0.005
LVEDV (mls) 123 ± 21 147 ± 38 132 ± 25 0.19 0.14 0.03
LVESV (mls) 43 ± 13 49 ± 19 51 ± 13 0.72 0.65 0.6
LV mass index (g/m2) 47 ± 5 72 ± 12 60 ± 8 <0.001 <0.0001 0.0003
RVEF (%) 53.2 ± 2 58.9 ± 7.2 54.8 ± 5.7 0.063 0.07 0.005
ECV 0.28 ± 0.03 0.33 ± 0.04 0.36 ± 0.03 <0.001 0.01 <0.001
LAV max index (ml/m2) 31 ± 8 50 ± 14 34 ± 9 <0.001 0.003 0.0009
LAV bac index (ml/m2) 19 ± 7 37 ± 12 30 ± 7 <0.001 0.001 0.03
LAV min index (ml/m2) 12 ± 5 20 ± 6 17 ± 4 0.009 0.009 0.22
LAPEF (%) 40 ± 9 26 ± 8 13 ± 9 <0.001 0.003 <0.0001
LACEF (%) 39 ± 5.2 46 ± 12 41 ± 9 0.26 0.18 0.3