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Table 1

From: CMR survey in Thalassemia Intermedia patients

  Non-transfusion-dependent Transfusion-dependent P
Age (years) 39.9 ± 11.5 39.2 ± 9.4 0.922
Sex (M/F) 67/47 66/72 0.083
Global heart T2* (ms) 38.8 ± 6.7 35.5 ± 9.2 0.014
MIO pattern, N (%):    
No MIO 92 (80.7) 96 (69.6) 0.103
Heterogeneous MIO with global T2* ≥ 20 ms 20 (17.5) 32 (23.2)  
Heterogeneous MIO with global T2* < 20 ms 1 (0.9) 3 (2.2)  
Homogeneous MIO 1 (0.9) 7 (5.1)  
LV end-diastolic volume index (ml/m2) 99.4 ± 19.6 92.9 ± 19.1 0.009
LV end-systolic volume index (ml/m2) 36.6 ± 11.4 34.9 ± 10.4 0.249
LV stroke volume index (ml/m2) 62.9 ± 12.4 58.6 ± 13.1 0.007
LV mass index (g/m2) 69.9 ± 13.9 63.9 ± 12.9 0.004
LV ejection fraction (%) 63.7 ± 6.8 62.5 ± 6.6 0.163
LV cardiac index (L/min/m2) 7.6 ± 2.3 6.5 ± 2.2 0.002
LGE, N (%) 20/105 (19) 32/122 (26.2) 0.199
RV end-diastolicvolume index (ml/m2) 92.0 ± 23.3 86.5 ± 20.8 0.048
RV end-systolic volume index (ml/m2) 32.7 ± 14.9 31.8 ± 11.3 0.571
RV stroke volume index (ml/m2) 58.5 ± 14.9 54.5 ± 14.3 0.017
RV ejection fraction (%) 64.7 ± 8.3 63.3 ± 7.5 0.168
  1. MIO = myocardial iron overload; LV = left ventricular; RV = right ventricular