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Table 1

From: Delineation of anthracyclines and herceptin induced cardiotoxicity using contrast enhanced CMR

  Baseline
(n = 24)
Post-chemo study 1
(n = 24)
Post-chemo study 2
(n = 13)
p
Ejection fraction (% ) (mean ± SD) 64 ± 6.5 63 ± 8 64 ± 7 NS
Indexed LVEDV (ml/m2) 68.3 ± 15 65 ± 17 69 ± 13 NS
Indexed LVESV (ml/m2) 25 ± 8 25 ± 9.13 25 ± 7 NS
Pre-Contrast T1 (ms) 976 ± 31 971 ± 36 984 ± 34 NS
Partition co-efficient (Λ)
(0,5,15, 20 min)
0.43 ± 0.30 0.41 ± 0.37 0.44 ± 0.36 NS
Partition co-efficient (Λ)
(0, 10, 15, 20 min)
0.42 ± 0.02 0.41 ± 0.03 0.44 ± 0.03 NS
Volume of distribution (Vd)
(0,5,10,15,20)
0.27 ± 0.02 0.27 ± 0.03 0.28 ± 0.02 NS
Average peak systolic radial strain (Err) (ms) 0.17 ± 0.02 0.17 ± 0.02 0.16 ± 0.03 NS
Average peak systolic circumferential strain (Ecc) (ms) -0.17 ± 0.03 -0.17 ± 0.03 -0.18 ± 0.04 NS
Average systolic strain rate (SSR) (ms) 1.07 ± 0.11 1.06 ± 0.2 1.14 ± 0.33 NS
Average diastolic strain rate (DSR) (ms) 0.96 ± 0.19 0.95 ± 0.27 0.90 ± 0.49 NS