Table 1
From: Delineation of anthracyclines and herceptin induced cardiotoxicity using contrast enhanced CMR
| Â | Baseline (n = 24) | Post-chemo study 1 (n = 24) | Post-chemo study 2 (n = 13) | p |
|---|---|---|---|---|
Ejection fraction (% ) (mean ± SD) | 64 ± 6.5 | 63 ± 8 | 64 ± 7 | NS |
Indexed LVEDV (ml/m2) | 68.3 ± 15 | 65 ± 17 | 69 ± 13 | NS |
Indexed LVESV (ml/m2) | 25 ± 8 | 25 ± 9.13 | 25 ± 7 | NS |
Pre-Contrast T1 (ms) | 976 ± 31 | 971 ± 36 | 984 ± 34 | NS |
Partition co-efficient (Λ) (0,5,15, 20 min) | 0.43 ± 0.30 | 0.41 ± 0.37 | 0.44 ± 0.36 | NS |
Partition co-efficient (Λ) (0, 10, 15, 20 min) | 0.42 ± 0.02 | 0.41 ± 0.03 | 0.44 ± 0.03 | NS |
Volume of distribution (Vd) (0,5,10,15,20) | 0.27 ± 0.02 | 0.27 ± 0.03 | 0.28 ± 0.02 | NS |
Average peak systolic radial strain (Err) (ms) | 0.17 ± 0.02 | 0.17 ± 0.02 | 0.16 ± 0.03 | NS |
Average peak systolic circumferential strain (Ecc) (ms) | -0.17 ± 0.03 | -0.17 ± 0.03 | -0.18 ± 0.04 | NS |
Average systolic strain rate (SSR) (ms) | 1.07 ± 0.11 | 1.06 ± 0.2 | 1.14 ± 0.33 | NS |
Average diastolic strain rate (DSR) (ms) | 0.96 ± 0.19 | 0.95 ± 0.27 | 0.90 ± 0.49 | NS |