| Controls N = 23 | SLE N = 23 | P value |
---|---|---|---|
Female sex, n (%) | 22 (92) | 22 (92) | 1.00 |
Age, years | 42 ± 9 | 41 ± 9 | 0.68 |
Current smokers, n (%) | 1 (4) | 3 (13) | 0.10 |
Hypertension, n (%) | 0 | 0 | - |
Diabetes, n (%) | 0 | 0 | - |
Hyperlipidaemia, n (%) | 1 (4) | 0 | - |
BMI, kg/m2 | 23 ± 3 | 28 ± 6 | < 0.001 |
SLEDAI (median, IQR) | N/A | 9 (7-14) | - |
ESR, mm/hr (median, IQR) | N/A | 6 (4-9) | - |
CRP, mg/L (median, IQR) | 1 (0-1) | 3 (2-6) | < 0.001 |
Hemoglobin, g/L | 13 ± 1 | 12 ± 1 | 0.37 |
Duration of SLE, years (median, IRQ) | N/A | 9 (6-14) | - |
Duration of DMARDs, years (median, IQR) | N/A | 7 (4-10) | - |
LVEDV indexed to BSA, ml/m2 | 79 ± 15 | 78 ± 13 | 0.91 |
LVESV indexed to BSA, ml/m2 | 21 ± 5 | 20 ± 6 | 0.43 |
LVEF, % | 74 ± 5 | 72 ± 5 | 0.17 |
LV Mass indexed to BSA, g/m2 | 49 ± 10 | 46 ± 11 | 0.21 |
LA size, mm | 26 ± 4 | 31 ± 5 | < 0.001 |
Mid SA circumferential strain | -19.3 ± 1.1 | -17.0 ± 1.6 | < 0.001 |
Peak diastolic circumferential strain rate (s-1) | 119 ± 15 | 79 ± 26 | < 0.001 |
Presence of LGE (%) | 0 | 5 (22) | - |
Volume fraction of LGE > 2SD (%) STIR T2 Ratio | 0 | 2.6 ± 0.2 | - |
STIR T2 Ratio | 1.5 ± 0.1 | 1.6 ± 0.1 | 0.06 |