From: Genotype positive hypertrophic cardiomyopathy is associated with myocardial perfusion abnormalities
Variable | Genotype POSITIVE | Genotype NEGATIVE | Significance (NS = not significant) |
---|---|---|---|
Number (%) | 102 (35%) | 186 (65%) | Â |
Male sex (%) | 75 (73.5%) | 137 (73.7%) | NS |
BSA (m2) | 1.97 (0.22) | 1.94 (0.22) | NS |
Age at CMR (years) | 54.6 (12.8) | 59.2 (13.4) | p = 0.005 |
Positive family history (%) | 22 (21.6%) | 35 (18.8%) | NS |
Length of follow up (months) | 37.6 (17.0) | 40.8 (20.4) | NS |
Dead (%) | 6 (5.9%) | 4 (2.2%) | NS |
LVEDV (mL) | 137.8 (33.6) | 134.2 (37.2) | NS |
LVESV (mL) | 34.4 (16.0) | 36.2 (19.4) | NS |
LVSV (mL) | 103.4 (25.6) | 98.0 (25.0) | NS (p = 0.08) |
LVEF (%) | 75.5 (8.5) | 74.1 (8.5) | NS |
LV Mass (g) | 174.8 (54.6) | 191.6 (66.2) | p = 0.030 |
LVEDVi (mL/m2) | 69.9 (14.5) | 69.0 (17.0) | NS |
LVESVi (mL/m2) | 17.4 (7.8) | 18.4 (9.2) | NS |
LV mass index (g/m2) | 88.1 (27.6) | 98.5 (31.2) | p = 0.005 |
STRESS PERFUSION SCAN POSITIVE | 65/79 (82.3%) | 87/135 (64.4%) | p = 0.015 |
Max wall thickness (mm) | 18.6 (3.7) | 19.1 (5.1) | NS |
Base most affected (%) | 68 (66.7%) | 103 (55.4%) | NS (p = 0.08) |
Apex most affected (%) | 15 (14.7%) | 39 (21.0%) | NS |
Septum most affected (%) | 92 (90%) | 154 (82.8%) | NS |
LGE score (%) | Â | Â | Â |
0 | 21 (21%) | 36 (20%) | NS |
1 | 36 (35%) | 64 (35%) | NS |
2 | 37 (36%) | 68 (37%) | NS |
3 | 8 (8%) | 16 (9%) | NS |