|
Age-matched controls (n = 21)
|
Hypertensive Non-LVH (n = 12)
|
Hypertensive LVH (n = 21)
|
---|
Sex
|
15 females; 6 males
|
6 females; 6 males
|
13 females; 8 males
|
Age (yrs)
|
52 ± 9
|
60 ± 14
|
55 ± 11
|
Systolic BP (mm Hg)
|
120 ± 16
|
136 ± 13^
|
156 ± 21*^
|
Diastolic BP (mm Hg)
|
69 ± 10
|
77 ± 12
|
88 ± 14^
|
Heart Rate
|
72 ± 12
|
72 ± 12
|
73 ± 16
|
Number of HTN meds
|
0
|
2.0 ± 1.3^
|
3.0 ± 1.5^
|
LV Mass (g)
|
75 ± 20
|
85 ± 23
|
147 ± 40*^
|
LVMI
|
41 ± 8
|
41 ± 9
|
71 ± 16*^
|
Partition Coefficient
|
0.43 ± 0.02
|
0.45 ± 0.02
|
0.48 ± 0.04*^
|
Volume of Distribution
|
0.26 ± 0.02
|
0.26 ± 0.02
|
0.28 ± 0.02*^
|
Mid-CircumferentialStrain
|
-0.17 ± 0.03
|
-0.16 ± 0.03
|
-0.12 ± 0.02*^
|
- [* = p < 0.05 vs. Non-LVH groups. ^ = p < 0.05 vs. controls.]