Figure 1
From: On the use of the "look-locker correction" for calculating T1 values from MOLLI
Simulated recovery curves for i) MOLLI (single LL block) (black) and ii) simplified MOLLI model where the bSSFP readout is replaced by a single excitation (blue). Curves begin at different levels of transverse magnetization due to 8 dummy TRs used for MOLLI. Because the simplified model ignores the effects of multiple excitations, the recovery is dominated by free T1 relaxation. Thus, the T1* of the actual MOLLI data will always be less than that of the simplified model. T1est will be similarly underestimated. Simulated parameters: T1/T2 = 1200/40 ms (normal myocardium), TR = 3.0 ms, 35° flip angle; 60 bpm heart rate