Figure 1

The effect of field heterogeneity on T1rho relaxation times in the phantom and in vivo. (A) Tilted rotating frame (TRF) Bloch simulations with random Gaussian noise. For the continuous wave 'rotary echo' spin lock pulse, measurement error was less than 1% for spin lock amplitudes greater than 400 Hz with minimal B₀ field heterogeneity. Between ω1 = 200-400 Hz, this error could rise to 10%. (B) B₀ and B₁ field maps, experimental and simulated T1rho images in the phantom with no field gradient (1) and with 100 mT/m gradient (2). (C) B₀ and B₁ field maps, experimental and simulated T1rho images in vivo.