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Table 2 Intra-observer and short-term inter-study variability for left ventricular volumes, mass and function in healthy adult subjects

From: Normative annual changes in left ventricular volumes, mass and function among healthy adults: a prospective cardiac magnetic resonance imaging study

Parameter

Variability

Bias ± SD

p

LoA

CV (%)

ICC (95% CI)

LVEF (%)

Intra-observer

Inter-study

1.00 ± 1.27

1.50 ± 1.76

0.11

0.09

-1.48 to 3.48

-1.95 to 4.95

1.8

2.4

0.99 (0.94 to 1.00)

0.98 (0.89 to 1.00)

LVEDV (mL)

Intra-observer

Inter-study

0.67 ± 3.62

0.50 ± 6.47

0.67

0.86

-6.43 to 7.77

-12.18 to 13.18

2.6

4.7

0.99 (0.95 to 1.00)

0.98 (0.85 to 1.00)

LVESV (mL)

Intra-observer

Inter-study

-0.83 ± 2.79

-1.33 ± 5.00

0.50

0.54

-6.30 to 4.64

-11.13 to 8.47

7.0

12.5

0.99 (0.93 to 1.00)

0.97 (0.78 to 1.00)

LVSV (mL)

Intra-observer

Inter-study

1.00 ± 2.97

1.67 ± 4.03

0.45

0.36

-4.82 to 6.82

-6.23 to 9.57

3.1

4.2

0.98 (0.85 to 1.00)

0.96 (0.74 to 0.99)

LVM (g)

Intra-observer

Inter-study

-0.33 ± 2.16

0.00 ± 3.03

0.21

1.00

-4.56 to 3.90

-5.94 to 5.94

1.5

2.1

0.99 (0.95 to 1.00)

0.99 (0.90 to 1.00)

  1. CV, coefficient of variability; ICC, intra-class correlation coefficient; LoA, limits of agreement; LVEF, left ventricular ejection fraction; LVEDV, left ventricular end diastolic volume; LVESV, left ventricular end systolic volume; LVSV, left ventricular stroke volume; LVM, left ventricular mass.