Figure 1

Representative images from the ischemic canine stress/rest studies (n=9) with high-grade LAD stenosis. (a,b): End-systolic adenosine stress and rest first-pass perfusion images (peak enhancement phase) using the developed real-time cine FPP technique. All of the stress-induced perfusion defect territories (arrows) show WMAs compared to the rest scan (larger end-systolic LV cavity area at stress compared to rest), consistent with the coronary steal (ischemic dilation) phenomenon. (c): standard SSFP cine end-systolic images (mid slice), showing a similar stress-versus-rest WMA pattern as in (a,b). This confirms that the real-time cine perfusion technique was capable of accurately capturing the wall motion at stress (i.e., achieving sufficiently high temporal resolution).