Figure 1

Presence of HIC within MI territories on SSFP images (A) and Predictive value of HIC on SSFP images for primary endpoint (B). A: Representatives SSFP and LGE images from two patients receiving ICD therapy; one who met the primary endpoint (Event+) and one who did not meet the primary endpoint (Event-). For the Event+ patient, blue arrows denote that MI region on Late Gadolinium Enhancement (LGE) imaging and the Hypo-Intense Core (HIC) region on SSFP imaging. In the Event- patient, no HIC were observed by SSFP within the MI region, indicated by the red arrow on LGE imaging. B: Corresponding ROC curves for LVEF, LVEF + Scar Volume, and LVEF + Scar Volume + HIC for the prediction of the primary endpoint. While the addition of Total Scar Volume alone did not improve the predictive accuracy over LVEF, the addition of HIC improved the AUC from 0.68 to ).87, suggesting additional prognostic value of HIC.