Figure 2

(A) Myofiber tracts in the lateral LV wall of a normal mouse. (B) Rightward shift of myofiber tracts in an aortic-banded mouse. The subepicardial fibers have assumed a more circumferential (yellow versus red) orientation. (C) Supertoroidal glyphs demonstrating the rightward shift of myofibers in the LV of an aortic-banded mouse. (D) Transmural evolution of HA in the lateral LV wall of normal and aortic-banded mice. A marked rightward shift is seen in the aortic-banded mice. Tracts in the RV free wall of (E) normal and (F) pulmonary-banded mice appear very similar with few circumferential fibers in either. (G) HA histograms of fibers in the RV free wall of the normal (blue) and pulmonary-banded (red) mice, revealing minimal changes in myofiber organization.