Table 2 Data comparing high and low cumulative anthracycline dose.
CARDIOVASCULAR MR DATA | Low dose <300mg/m2 (n =22) | High dose >300mg/m2 (n = 8) | p Value |
|---|---|---|---|
LVEDV index (ml/m2) | 71 ±11 | 80 ±14 | 0.1 |
LVESV index (ml/m2) | 28 ±8 | 36 ±6 | *0.03 |
LV EF (%) | 65 ±5 | 54 ±6 | *0.01 |
LV Mass index (g/m2) | 58 ±11 | 59 ±9 | 0.94 |
RVEDV index (ml/m2) | 70 ±10 | 69 ±17 | 0.87 |
RVESV index (ml/m2) | 28 ±15 | 26 ±7 | 0.77 |
RV EF (%) | 65 ±5 | 62 ±2 | 0.46 |
MAPSE (cm) | 13 ±2.1 | 13 ±4.1 | 0.72 |
Left Atrial Area (cm2) | 21 ±3 | 21 ±4 | 0.94 |
Native T1 | 960 ±39 | 992 ±24 | *0.05 |
Native blood pool T1 | 1464 ±79 | 1527±38 | *0.05 |
Extracellular volume fraction | 0.25 ±0.02 | 0.28 ±0.05 | *0.02 |
LGE | 1 (14) | 1 (5) | Â |