Low encoding frequencies accurately quantify cardiac mechanics while minimizing phase wrapping in 2D cine DENSE with through-plane dephasing

Table 1 Summary statistics (all 15 subjects) showing good agreement for encoding frequency between 0.04 and 0.10 cycles/mm. Larger biases, 95% LOA, and CoV were observed for encoding frequency of 0.02 cycles/mm.

E(k_e) *	Circumferential Strain				Radial Strain				Twist (Degrees)
	Bias	95% LOA	Mean CoV	p-value	Bias	95% LOA	Mean CoV	p-value	Bias	95% LOA	Mean CoV	p-value
E(0.10) - E(0.02)	-1.9%	±5.3%	10%	0.02**	3.1%	±21.9%	22%	0.31	-0.50	±1.89	12%	0.07
E(0.10) - E(0.04)	0.0%	±3.2%	4%	1.00	-1.0%	±13.5%	10%	0.57	-0.02	±1.26	7%	0.91
E(0.10) - E(0.06)	0.6%	±2.9%	4%	0.15	0.6%	±11.2%	10%	0.69	-0.19	±0.79	4%	0.09
E(0.10) - E(0.08)	0.3%	±3.0%	4%	0.45	-1.8%	±9.7%	9%	0.19	-0.05	±0.71	4%	0.59
Inter-test	-0.3%	±2.0%	3%	0.23	0.4%	±12.1%	10%	0.81	0.00	±0.93	5%	0.99

*Represents peak strain and twist measured using a particular encoding frequency.
**Statistical significance between peak measures of mechanics using paired-sample t-test at significance level α = 0.05.
***LOA - Limits of Agreement, CoV - Coefficient of Variation.

ISSN: 1532-429X