Figure 1

A): a) Optical microscopy of the human pluripotent cell-derived cardiomyocytes (iCMs); b) Confocal image of the iCMs immunolabeled for alpha-Actinitn (green), cardiac TroponinT (red), Connexin43 (violet) and nuclei (blue); c) flow cytometry results showing the existence of cTnT and VCAM1 positive iCMs; d) spontaneous atomic force microscopy (AFM) measurement and calcuim flux in iCMs B) Bioluminescence of RG Luciferase activity from human cells in heart at week 4 after transplant. B) BLI signal of the mice after 2 weeks (top panel) and 4 weeks (bottom panel) of iCM injection. C) MEMRI images of iCMs injection (after 2 (top panel) and 4 weeks (bottom panel)) for myocardial infarct.