Figure 1

Representative short-axis images obtained from a canine (A) and the statistical relations between 2D BH and 3D MoCo for T2 and edema volume across all animals on day 4 post myocardial infarction (B-E). (A) Slice-matched T2 maps from 2D BH and 3D FB MoCo, as well as LGE images obtained from a canine at the basal, mid ventricle (Mid) and apical sections are shown. Note the close correspondence between hyperintense regions in LGE images (yellow arrows). Also not that the 2D BH images are blurrier due to cardiac motion (from single-shot acquisitions in the presence of high heart rates in canines with recent infarction), which is not the case with the proposed approach. (B) Linear regression analysis between T2 values (edematous territories and remote myocardium) of slice-matched 3D FB MoCo and 2d BH acquisitions and the corresponding Bland-Altman analysis are shown in panels B and C, respectively. Linear regression: y = 0.9 x – 3.4, where y = T2 from 2D BH acquisitions, with R2 = 0.88, p<0.05. Linear regression analysis between slice-matched 3D FB MoCO and 2D BH acquisions to Edema volume and the corresponding Bland-Altman analysis are shown in panels D and E, respectively. Linear regression: y1 = 1.1 x1 -2.4, where y1 = Edema volume from 3D FB MoCO and x1 = Edema volume from 2D BH acquisitions, with R2 = 0.96, p<0.05.