- Walking poster presentation
- Open Access
Non - invasive right ventricular efficiency using 4D flow MRI
© Roldán-Alzate et al; licensee BioMed Central Ltd. 2015
- Published: 3 February 2015
- Right Ventricular
- Pulmonary Arterial Hypertension
- Stroke Work
- Right Heart Catheterization
- Right Ventricular Volume
Pulmonary arterial hypertension (PH) is a progressive disease of increased resistance to flow through the lungs, leading to right ventricular (RV) failure . MRI is increasingly used to assess right ventricular (RV) function in PH. RV stroke work (SW) based on invasive pressure and volume measurements, is used to assess ventricular work. Determining RV work from MRI could enable a more complete characterization of RV and PA interactions in PH. The purpose of this study was to non-invasively estimate RV work from simultaneously acquired RV volume (VRV) and pulmonary artery flow (QPA) using a 4D flow-sensitive MRI sequence in a canine model.
QMPA - VRV loop area estimated noninvasively using 4D flow MRI can be used to evaluate right ventricular stroke work. The results from this study indicate that 4D flow-sensitive MRI with PC VIPR can also be used to estimate right ventricular work, complementing the analysis of alterations in flow patterns in the heart and pulmonary arteries in patients with cardiopulmonary disease, however more studies need to be done for validation of the model.
NIH R01HL072260, NIH R01HL086939, and the Department of Radiology.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.