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Table 2 Myocardial structure, function and perfusion in RA patients and controls

From: Impaired myocardial perfusion in rheumatoid arthritis is associated with impaired strain, strain rate, disease activity and myocardial oedema: a cardiovascular magnetic resonance study

 

Controls N=55

RA N=55

P value

LVEDV indexed to BSA, ml/m2

78 ± 15

79 ± 15

0.92

LVESV indexed to BSA, ml/m2

22 ± 14

22 ± 8

0.96

LVEF, %

74 ± 4

72 ± 7

0.45

LV Mass indexed to BSA, g/m2

54 ± 11

55 ± 11

0.64

LA size, mm

27 ± 5

32 ± 6

<0.001

Mid SA circumferential strain

-18.7 ± 1.2

-17.0 ± 1.1

<0.001

Peak diastolic circumferential strain rate (s-1)

115 ± 21

82 ± 19

<0.001

Presence of LGE (%)

0

27 (49)

-

Volume fraction of LGE>2SD (%)

0

3.8 ± 0.3

-

Global myocardial T2 SI Ratio

1.5 ± 0.1

1.7 ± 0.3

<0.001

Volume fraction of oedema by T2 (%)

0

20 (8-33)

-

Average myocardial T1, ms

958 ± 26

971 ± 23

<0.001

Volume fraction of T1>990ms (%)

1 (1-6)

32 (18-49)

<0.001

ECV (%)

27.4 ± 2.9

30.1 ± 3.2

<0.001

Rest RPP

8, 982 ± 1, 716

8, 807 ± 1, 347

0.13

Stress RPP

11, 360 ± 1, 835

12, 530 ± 2, 547

<0.001

MPRI

1.9 ± 0.4

1.5 ± 0.3

<0.001

Proportion of non-segmental perfusion defects (%)

0

27 (49)

-

  1. Continuous data are mean ± SD unless otherwise indicated.
  2. ECV, extracellular volume; LA, left atrium; LGE, late gadolinium enhancement; LV, left ventricle/ventricular; LVEDV, left ventricular end-diastolic volume; LVEF, left ventricular ejection fraction; LVESV, left ventricular end-systolic volume; MPRI, myocardial perfusion reserve index; RA, rheumatoid arthritis; RPP, rate pressure product; SA, short axis; SI, signal intensity