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Table 2 Myocardial structure, function and perfusion in RA patients and controls

From: Impaired myocardial perfusion in rheumatoid arthritis is associated with impaired strain, strain rate, disease activity and myocardial oedema: a cardiovascular magnetic resonance study

  Controls N=55 RA N=55 P value
LVEDV indexed to BSA, ml/m2 78 ± 15 79 ± 15 0.92
LVESV indexed to BSA, ml/m2 22 ± 14 22 ± 8 0.96
LVEF, % 74 ± 4 72 ± 7 0.45
LV Mass indexed to BSA, g/m2 54 ± 11 55 ± 11 0.64
LA size, mm 27 ± 5 32 ± 6 <0.001
Mid SA circumferential strain -18.7 ± 1.2 -17.0 ± 1.1 <0.001
Peak diastolic circumferential strain rate (s-1) 115 ± 21 82 ± 19 <0.001
Presence of LGE (%) 0 27 (49) -
Volume fraction of LGE>2SD (%) 0 3.8 ± 0.3 -
Global myocardial T2 SI Ratio 1.5 ± 0.1 1.7 ± 0.3 <0.001
Volume fraction of oedema by T2 (%) 0 20 (8-33) -
Average myocardial T1, ms 958 ± 26 971 ± 23 <0.001
Volume fraction of T1>990ms (%) 1 (1-6) 32 (18-49) <0.001
ECV (%) 27.4 ± 2.9 30.1 ± 3.2 <0.001
Rest RPP 8, 982 ± 1, 716 8, 807 ± 1, 347 0.13
Stress RPP 11, 360 ± 1, 835 12, 530 ± 2, 547 <0.001
MPRI 1.9 ± 0.4 1.5 ± 0.3 <0.001
Proportion of non-segmental perfusion defects (%) 0 27 (49) -
  1. Continuous data are mean ± SD unless otherwise indicated.
  2. ECV, extracellular volume; LA, left atrium; LGE, late gadolinium enhancement; LV, left ventricle/ventricular; LVEDV, left ventricular end-diastolic volume; LVEF, left ventricular ejection fraction; LVESV, left ventricular end-systolic volume; MPRI, myocardial perfusion reserve index; RA, rheumatoid arthritis; RPP, rate pressure product; SA, short axis; SI, signal intensity