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Table 2 Myocardial structure, function and perfusion in SSc patients and controls

From: Impaired myocardial perfusion is associated with extracellular volume expansion, disease activity and impaired strain and strain rate in systemic sclerosis: a cardiovascular magnetic resonance study

  Controls N=17 SSc N=17 P value
LVEDV indexed to BSA, ml/m2 78 ± 17 74 ± 11 0.15
LVESV indexed to BSA, ml/m2 21 ± 5 18 ± 5 0.06
LVEF, % 74 ± 6 73 ± 5 0.36
LV Mass indexed to BSA, g/m2 51 ± 12 51 ± 8 0.89
LA size, mm 28 ± 5 37 ± 6 <0.001
Mid SA circumferential strain -18.7 ± 1.0 -17.0 ± 1.7 <0.001
Peak diastolic circumferential strain rate (s-1) 114 ± 16 86 ± 24 <0.001
Presence of LGE (%) 0 10 (59) -
Volume fraction of LGE>2SD (%) 0 2.6 ± 0.3 -
Global myocardial T2 SI Ratio 1.5 ± 0.2 1.7 ± 0.4 0.08
Volume fraction of oedema by T2 (%) 0 18 (7-23) -
Average myocardial T1, ms 958 ± 22 1, 008 ± 28 <0.001
Volume fraction of T1>990ms (%) 0 59 (43-71) -
ECV (%) 27.9 ± 2.4 35.4 ± 4.7 <0.001
Rest RPP 7, 989 ± 1, 280 8, 478 ± 1, 829 0.37
Stress RPP 11, 732 ± 1, 789 11, 980 ± 1, 790 0.69
MPRI 2.0 ± 0.4 1.5 ± 0.3 <0.001
Proportion of non-segmental perfusion defects (%) 0 7 (41) -
  1. Continuous data are mean ± SD unless otherwise indicated.
  2. ECV, extracellular volume; LA, left atrium; LGE, late gadolinium enhancement; LV, left ventricle/ventricular; LVEDV, left ventricular end-diastolic volume; LVEF, left ventricular ejection fraction; LVESV, left ventricular end-systolic volume; MPRI, myocardial perfusion reserve index; RPP, rate pressure product; SA, short axis; SI, signal intensity, SSc, systemic sclerosis