From: Sarcoidosis: comprehensive CMR evaluation and major adverse cardiac events
 |  | Major Adverse Cardiac Event | Mortality | ||
---|---|---|---|---|---|
Variable | Value | Hazard Ratio | P | Hazard Ratio | P |
Age,y* | 52 ± 11 | 1.3(0.9-1.8) | 0.168 | 2.1(1.1-4.4) | 0.033 |
Male | 51(55%) | 1.4(0.7-3.1) | 0.350 | 0.7(0.15-3.0) | 0.601 |
AV block+ | 7(8%) | 8.8(3.5-21.9) | < 0.001 | 6.1(1.2-31.4) | 0.032 |
Basal LV thinning+ | 3(3%) | Not defined | 0.989 | Not defined | 0.995 |
LV ejection fraction < 50%+ | 17(18%) | 3.1(1.4-6.5) | 0.004 | 6.2(1.4-27.5) | 0.018 |
Ventricular ectopy+ | 9(10%) | 5.0(2.1-11.9) | < 0.001 | Not defined | 0.995 |
Right bundle branch block+ | 16(17%) | 3.2(1.4-7.1) | 0.005 | 4.9(1.1-22.3) | 0.038 |
Axis deviation+ | 19(20%) | 2.4(1.4-4.2) | 0.002 | 3.4(1.3-8.9) | 0.011 |
Pathologic Q waves+ | 7(8%) | 4.1(1.7-10.2) | 0.002 | 14.6(3.2-66.9) | < 0.001 |
LV wall motion abnormality+ | 11(12%) | 3.1(1.3-7.3) | 0.011 | 10.1(2.3-45.2) | 0.003 |
Heart failure | 13(14%) | 2.5(1.1-5.8) | 0.027 | 4.8(1.1-21.7) | 0.040 |
Coronary artery disease | 6(6%) | 2.0(0.6-6.5) | 0.267 | 7.8(1.5-40.6) | 0.014 |
Diabetes mellitus | 12(13%) | 0.8(0.2-2.6) | 0.678 | 1.1(0.1-9.4) | 0.912 |
Hypertension | 33(35%) | 2.1(1.0-4.3) | 0.056 | 12.2(1.5-101.6) | 0.021 |
Left atrial AP dimension, mm* | 35 ± 8 | 1.0(0.6-1.5) | 0.940 | 3.6(1.7-7.6) | < 0.001 |
Right atrial 4-chamber dimension, mm* | 51 ± 8 | 0.7(0.4-1.2) | 0.193 | 2.4(1.0-5.3) | 0.040 |
LV end diastolic volume, ml* | 163 ± 46 | 1.1(1.0-1.2) | 0.001 | 1.2(1.1-1.4) | 0.007 |
LV end diastolic volume index, ml/m2* | 82 ± 20 | 1.4(1.2-1.6) | < 0.001 | 1.4(1.1-1.9) | 0.010 |
LV end systolic volume, ml* | 89 ± 40 | 1.1(1.1-1.2) | < 0.001 | 1.3(1.1-1.4) | < 0.001 |
LV ejection fraction,%* | 57 ± 11 | 0.6(0.5-0.8) | 0.001 | 0.5(0.3-0.8) | 0.008 |
LV mass, g* | 111 ± 42 | 1.1(1.0-1.2) | 0.056 | 1.3(1.1-1.5) | < 0.001 |
RV end diastolic volume, ml* | 154 ± 42 | 1.0(1.0-1.1) | 0.318 | 1.1(0.9-1.3) | 0.446 |
RV end diastolic volume index, ml/m2* | 77 ± 16 | 1.2(1.0-1.5) | 0.074 | 1.3(0.8-2.1) | 0.393 |
RV end systolic volume, ml* | 69 ± 28 | 1.1(1.0-1.2) | 0.236 | 1.2(1.0-1.4) | 0.100 |
RV ejection fraction, %* | 56 ± 7 | 0.8(0.5-1.4) | 0.474 | 1.0(0.3-3.4) | 0.950 |
Presence of LGE+ | 15(16%) | 2.2(0.9-5.2) | 0.072 | 0.9(0.1-7.8) | 0.956 |
Number of segments with LGE | 1 ± 3 | 1.1(1.0-1.3) | 0.042 | 1.2(0.9-1.4) | 0.204 |
Steroid therapy | 37(40%) | 0.5(0.2-1.1) | 0.087 | 2.7(0.5-14.9) | 0.248 |