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Table 1 The coefficients (and associated p-values) from logistic regression models assessing the association between prior cardiovascular disease and coronary heart disease with myocardial fibrosis indices.

From: Association of myocardial fibrosis and prior cardiovascular disease: the multi-ethnic study of atherosclerosis (MESA)

 

Composite Cardiovascular Disease

Coronary Heart Disease

 

No of events/total population

Univariate

Model 1

Model 2

No of events/total population

Univariate

Model 1

Model 2

LGE +ve

143/1840

2.06 (<0.01)

1.64 (<0.01)

1.42 (<0.01)

69/1840

2.53 (<0.01)

2.04 (<0.01)

2.24 (<0.01)

Pre-contrast T1 (ms) × 10^(-3)

108/1344

0.4 (0.87)

-0.7(0.77)

-1.3 (0.59)

55/1344

-3.0 (0.26)

-3.1 (0.30)

-3.7 (0.19)

Post-contrast T1 12' (ms) × 10^(-3)

108/1345

-6.8 (<0.01)

-9.0 (<0.01)

-8.0 (0.01)

55/1345

-8.3 (0.013)

-14.8 (<0.01)

-12.2 (<0.01)

Post-contrast T1 25' (ms) × 10^(-3)

108/1330

-7.5 (<0.01)

-9.0 (<0.01)

-8.2 (0.01)

55/1330

-10.7 (<0.01)

-17.9 (<0.01)

-16.1 (<0.01)

ECV (%)

72/681

0.06 (0.13)

0.05 (0.26)

0.02 (0.58)

36/681

0.04 (0.40)

0.06 (0.29)

0.02 (0.73)

  1. Model 1: age, gender and race; and traditional cardiovascular risk factors - Model 2: Model 1 + blood pressures, hypertension/lipid medication use, diabetes, HDL and total cholesterol, body mass index, smoking status, glomerular filtration rate (post-contrast T1 only).