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Figure 2 | Journal of Cardiovascular Magnetic Resonance

Figure 2

From: Towards reliable myocardial blood-oxygen-level-dependent (BOLD) CMR using late effects of regadenoson with simultaneous 13n-ammonia pet validation in a whole-body hybrid PET/MR system

Figure 2

13N-Ammonia PET Myocardial Blood Flow and BOLD Response at 10 mins post regadenoson administration (p.r.a.). Representative rest and stress (10 mins p.r.a) short-axis PET Myocardial Blood Flow (MBF) and myocardial BOLD T2 pages are shown in panels A and C. Both PET and BOLD images shown significant increase in MBF and BOLD response, respectively, at 10 mins p.r.a. compared to rest. Box plot of rest and stress MBF and myocardial T2 across all animals are shown in panels B and D, respectively. Mean increase in MBF by a factor of 3.0 and a 9% T2 elevation were observed on the PET and T2 maps acquired at 20 min p.r.a. relative to rest. Results from regression analysis showed good correlation between PET myocardial perfusion reserve (MBF(stress)/MBF(rest)) and Myocardial BOLD Response (R = 0.7, p < 0.05; panel E).

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