A: An example of pre-CE CHIP was found at middle LAD as localized on the bright-blood images. XA showed significant stenosis (70%) at that location. OCT showed large signal-poor area suggestive of possible lipid core and/or intra-plaque hemorrhage (yellow arrow). B: An example of post-CE CHIP with diffuse wall enhancement at proximal RCA as localized on the bright-blood images. XA showed only mild stenosis (30%) at that location. OCT showed strong multi-focal back reflections and signal heterogeneity within the overlaying tissue suggestive of high macrophage density (yellow arrows). C: Coronary plaques with high-risk features as classified by OCT tended to be hyper-intensive on CATCH images. Star signs (*) denote statistical significance (p < 0.05). Positive sign (+) and negative sign (-) denote lesion groups with corresponding OCT grading. Plaque hyper-intensity is presented in terms of plaque to myocardium ratio (PMR) as described previously .