Table 1 Resting and peak values during MR-CPET
From: MR-Augmented Cardiopulmonary Exercise Testing- a proof of concept in Sickle Cell Disease (SCD)
Variable | Normal Mean (range) | Disease Mean (range) | P-value |
|---|---|---|---|
Resting VO2, Lmin-1 | 0.210 (0.17- 0.25) | 0.231 (0.19-0.27) | 0.38 |
Peak VO2, Lmin-1 | 1.1 (0.9- 1.3) | 0.7 (0.56- 0.76) | 0 < 0.001** |
Resting cardiac output, Lmin-1 | 6.7 (5.9-7.5) | 8.1 (7.1-9.2) | < 0.05* |
Peak cardiac output, Lmin-1 | 13 (12-14) | 12 (11-13) | < 0.05* |
Resting stroke volume, mlbeat-1 | 98 (84-111) | 109 (98-119) | 0.17 |
Peak Stroke volume, mlbeat-1 | 101 (81-120) | 116 (105- 27) | 0.16 |
Resting heart rate, bpm | 66 (56-77) | 77 (72-81) | 0.067 |
Max heart rate, bpm | 138 (124-152) | 120 (111-129) | < 0.05* |
Resting tissue extraction, mlO2ml-1blood | 0.31 (0.26-0.35) | 0.28 (0.24-0.32) | 0.34 |
Peak tissue extraction, mlO2ml-1blood | 0.90 (0.79-1.02) | 0.51 (0.43- 0.59) | < 0.001** |