Age-related association of aortic arch pulse wave velocity assessed by MRI with incident cardiovascular events: the multi-ethnic study of atherosclerosis (MESA)

Table 1 Hazard Ratios of the logPWV for Cardiovascular Events Stratified by Age Groups no. of events

	no. of events	Unadjusted		Model 1		Model 2
		HR (95% CI)	p	HR (95% CI)	p	HR (95% CI)
All participants (n = 3,529)	427	1.26 (1.16-1.38)	<0.001	1.06 (0.97-1.17)	0.21	1.03 (0.94-1.14)	0.46
Age categories
45-54 years old (n-1,027)	53	1.59 (1.23-2.06)	<0.001	1.48 (1.15-1.92)	0.002	1.47 (1.10-1.97)	0.009
55-64 years old (n-946)	96	1.10 (0.90-1.35)	0.35	1.08 (0.89-1.33)	0.43	0.99 (0.79-1.24)	0.94
65-75 years old (n-1,071)	169	1.05 (0.90-1.22)	0.51	1.03 (0.88-1.20)	0.75	1.01 (0.87-1.19)	0.87
75-84 years old (n = 485)	109	0.94 (0.78-1.14)	0.55	0.95 (0.78-1.15)	0.56	1.00 (0.83-1.22)	0.98

Hazard ratios are indicated per 1SD higher logPWV. Adjustment was performed for the following risk factors: model 1 = adjusted for age, gender, and race; model 2 = model 1 + mean blood pressure, antihypertensive medication use, diabetes, smoking, total cholesterol, HDL cholesterol, BMI.
HR indicates hazard ratio; BMI, body mass index; HDL, high density lipoprotein; PWV, pulse wave velocity; logPWV, log-transformed PWV

ISSN: 1532-429X