Figure 1
From: A simple clinical model to predict presence of myocardial fibrosis in patients with aortic stenosis
Using the model based on the platelet count, urea level, NT-Pro BNP level and LVEF the probability of any fibrosis can be calculated for each patient. Depending on the clinical setting the model allows for variable cut-off values to adjust sensitivity and specificity according to clinical requirements. For example, a probability cut-off of 0.50 will give 90% sensitivity of predicting any fibrosis with 55% specificity; whereas a cut-off value of 0.90 will give 50% sensitivity with a specificity of 93%.