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Table 1 Baseline clinical and demographic characteristics of the study cohort stratified according to the presence/absence of severe microvascular dysfunction

From: Coronary microvascular ischemia in hypertrophic cardiomyopathy - a pixel-wise quantitative cardiovascular magnetic resonance perfusion study

 

Non-severe

Severe

All patients

 

Characteristic – n (%)

24 (68.6)

11 (31.4)

35

P value

Median age – years (IQR)

58.9 (52.3, 67.5)

52.0 (42.5, 63.6)

57.1 (48.5, 66.6)

0.256

Male sex – n (%)

18 (75.0)

7 (63.6)

25 (71.4)

0.490

Apical phenotype – n (%)

4 (16.7)

2 (18.2)

6 (17.1)

0.912

Risk factors for SCD

    

  Sustained VT/VF – n (%)

0 (0)

1 (9.1)

1 (2.9)

0.134

  Family history of SCD – n (%)

2 (8.3)

1 (9.1)

3 (8.6)

0.941

  Wall thickness ≥30 mm – n (%)

1 (4.2)

1 (9.1)

2 (5.7)

0.560

  Resting LVOT obstruction ≥30 mmHg – n (%)

1 (4.2)

3 (27.3)

4 (11.4)

0.046

  Non-sustained VT – n (%)

3 (12.5)

0 (0)

3 (8.6)

0.220

  Unexplained syncope – n (%)

3 (12.5)

1 (9.1)

4 (11.4)

0.769

Number of risk factors for SCD – n (%)

    

  0

14 (58.3)

5 (45.5)

19 (54.3)

0.296

  1

10 (41.7)

5 (45.5)

15 (42.9)

 

  2+

0 (0.0)

1 (9.1)

1 (2.9)

 

NYHA functional class – n (%)

    

  I

16 (66.7)

8 (72.7)

24 (68.6)

0.720

  II

8 (33.3)

3 (27.3)

11 (31.4)

 

  III

0 (0)

0 (0)

0 (0)

 

  IV

0 (0)

0 (0)

0 (0)

 

Medications at baseline – n (%)

    

  β-blocker

14 (58.3)

6 (54.6)

20 (57.1)

0.833

  Ca2+-channel blocker

0 (0)

1 (9.1)

1 (2.9)

0.134

  1. QR = Interquartile Range; SCD = Sudden Cardiac Death; VT = Ventricular Tachycardia; VF = Ventricular Fibrillation; LVOT = Left Ventricular Outflow Tract; NYHA = New York Heart Association.