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Table 1 Baseline subject characteristics

From: Multiparametric cardiovascular magnetic resonance surveillance of acute cardiac allograft rejection and characterisation of transplantation-associated myocardial injury: a pilot study

 

Transplant patients (n = 22)

Healthy volunteers (n = 10)

p value

Male

17 (77%)

7 (70%)

0.660

Age (years)

49 ± 10

49 ± 8

0.961

Non-white

2 (9%)

1 (10%)

0.676

BSA (m2)

1.86 ± 0.20

1.94 ± 0.19

0.290

BMI (kg/m2)

24.7 ± 3.6

25.7 ± 4.1

0.484

eGFR (mL/min/m2)

61 ± 24

89 ± 13

<0.001

HR (bpm)

89 ± 15

60 ± 6

<0.001

Systolic BP (mmHg)

135 ± 17

111 ± 8

<0.001

Indication for transplant

   

 DCM

12 (55%)

-

 

 IHD

6 (27%)

-

 

 ARVC

2 (9%)

-

 

 HCM

1 (5%)

-

 

 Re-transplant

1 (5%)

-

 

Pregnancy prior to transplantation

3 (14%)

-

 

VAD prior to transplantation

1 (5%)

-

 

Donor age (years)

42 ± 7

-

 

Donor male

17 (77%)

-

 

Donor: recipient gender match

18 (82%)

-

 

Donor cause of death

   

 ICH

13 (59%)

-

 

 Head trauma

5 (23%)

-

 

 Other

4 (18%)

-

 

CMV donor pos., recipient neg.

5 (23%)

-

 

Ischaemic time (min)

184 ± 52

-

 

Induction immunosuppression

   

 rATG

21 (95%)

-

 

 Basiliximab

1 (5%)

-

 

Initial immunosuppression regime

   

 Cyclosporine/prednisolone/MMF

21 (95%)

-

 

 Tacrolimus/prednisolone/MMF

1 (5%)

-

 

ICU stay (days)

17 ± 19

-

 

Hospital stay (days)

36 ± 23

-

 
  1. BSA indicates body surface area; BMI body mass index; eGFR estimated glomerular filtration rate; HR heart rate; BP blood pressure; DCM indicates dilated cardiomyopathy; IHD ischemic heart disease; ARVC arrhythmogenic right ventricular cardiomyopathy; HCM hypertrophic cardiomyopathy; (Re-transplant: this patient suffered immediate graft failure and therefore underwent a second transplantation); VAD ventricular assist device; ICH spontaneous intracranial haemorrhage; CMV cytomegalovirus; rATG rabbit antithymocyte globulin; MMF Mycophenolate mofetil; ICU intensive care unit.