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Table 3 CMR findings displayed according to scan number

From: Multiparametric cardiovascular magnetic resonance surveillance of acute cardiac allograft rejection and characterisation of transplantation-associated myocardial injury: a pilot study

  Scan 1 (6.9 weeks) Scan 2 (10.9 weeks) Scan 3 (16.6 weeks) Scan 4 (22.3 weeks) p value Healthy volunteers
LVEDVI (mL/m2) 83.2 ± 20.3 83.4 ± 23.2 83.7 ± 22.6 82.6 ± 19.9 0.979 85.9 ± 8.1
LVESVI (mL/m2) 35.3 ± 21.1 35.8 ± 23.6 34.5 ± 21.2 33.5 ± 19.4 0.423 28.5 ± 4.3
LVEF (%) 59.5 ± 13.2 60.1 ± 14.2 61.1 ± 13.9 61.3 ± 12.2 0.216 66.9 ± 4.2
LVMI (g/m2) 63.6 ± 15.7 62.5 ± 12.9 62.1 ± 12.8 59.3 ± 11.9 0.001 46.4 ± 7.3
εcc (%) −12.4 ± 3.8 −13.5 ± 2.9 −14.2 ± 3.8 −14.4 ± 3.0 0.024 −20.7 ± 1.0
Peak systolic SR (1/s) −1.05 ± 0.33 −1.03 ± 0.27 −1.07 ± 0.33 −1.05 ± 0.30 0.669 −1.17 ± 0.14
Early diastolic SR (1/s) 0.29 ± 0.13 0.25 ± 0.10 0.23 ± 0.12 0.25 ± 0.15 0.499 0.37 ± 0.20
Normalised twist (°/mm) 0.26 ± 0.10 0.25 ± 0.10 0.27 ± 0.11 0.27 ± 0.08 0.709 0.34 ± 0.12*
Torsion (mm) 7.68 ± 2.89 7.16 ± 2.73 7.78 ± 3.19 7.59 ± 2.24 0.761 8.99 ± 3.11
Time to peak torsion (% AVC) 101.0 ± 11.0 97.1 ± 7.2 97.9 ± 6.3 96.5 ± 9.3 0.466 96.4 ± 5.5
Native T1 (ms) 1109 ± 53 1089 ± 62 1084 ± 70 1063 ± 40 <0.001 989 ± 46
T2 (ms) 58.7 ± 3.4 57.1 ± 3.4 56.9 ± 2.9 55.9 ± 2.9 0.003 54.1 ± 2.0
Resting MBF (mL/min/g) - 0.85 ± 0.12 - 0.86 ± 0.16 0.150 0.74 ± 0.10
Stress MBF (mL/min/g) - 1.21 ± 0.18 - 1.37 ± 0.26 0.172 1.81 ± 0.29
MPR - 1.44 ± 0.22 - 1.62 ± 0.35 0.023 2.46 ± 0.34
ECV - 30.1 ± 0.5 - 28.0 ± 1.6 <0.001 25.3 ± 0.18
  1. Time between transplantation and scan is given in brackets.
  2. p values refer to the significance of the difference between scans. The significance of the difference between healthy volunteers and scan 4 is denoted by *(p < 0.05) and (p < 0.01). MBF indicates myocardial blood flow; MPR myocardial perfusion reserve; LGE late gadolinium enhancement; ECV myocardial extracellular volume. Other abbreviations as per Table 2.