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Table 3 CMR findings displayed according to scan number

From: Multiparametric cardiovascular magnetic resonance surveillance of acute cardiac allograft rejection and characterisation of transplantation-associated myocardial injury: a pilot study

 

Scan 1 (6.9 weeks)

Scan 2 (10.9 weeks)

Scan 3 (16.6 weeks)

Scan 4 (22.3 weeks)

p value

Healthy volunteers

LVEDVI (mL/m2)

83.2 ± 20.3

83.4 ± 23.2

83.7 ± 22.6

82.6 ± 19.9

0.979

85.9 ± 8.1

LVESVI (mL/m2)

35.3 ± 21.1

35.8 ± 23.6

34.5 ± 21.2

33.5 ± 19.4

0.423

28.5 ± 4.3

LVEF (%)

59.5 ± 13.2

60.1 ± 14.2

61.1 ± 13.9

61.3 ± 12.2

0.216

66.9 ± 4.2

LVMI (g/m2)

63.6 ± 15.7

62.5 ± 12.9

62.1 ± 12.8

59.3 ± 11.9

0.001

46.4 ± 7.3†

εcc (%)

−12.4 ± 3.8

−13.5 ± 2.9

−14.2 ± 3.8

−14.4 ± 3.0

0.024

−20.7 ± 1.0†

Peak systolic SR (1/s)

−1.05 ± 0.33

−1.03 ± 0.27

−1.07 ± 0.33

−1.05 ± 0.30

0.669

−1.17 ± 0.14

Early diastolic SR (1/s)

0.29 ± 0.13

0.25 ± 0.10

0.23 ± 0.12

0.25 ± 0.15

0.499

0.37 ± 0.20

Normalised twist (°/mm)

0.26 ± 0.10

0.25 ± 0.10

0.27 ± 0.11

0.27 ± 0.08

0.709

0.34 ± 0.12*

Torsion (mm)

7.68 ± 2.89

7.16 ± 2.73

7.78 ± 3.19

7.59 ± 2.24

0.761

8.99 ± 3.11

Time to peak torsion (% AVC)

101.0 ± 11.0

97.1 ± 7.2

97.9 ± 6.3

96.5 ± 9.3

0.466

96.4 ± 5.5

Native T1 (ms)

1109 ± 53

1089 ± 62

1084 ± 70

1063 ± 40

<0.001

989 ± 46†

T2 (ms)

58.7 ± 3.4

57.1 ± 3.4

56.9 ± 2.9

55.9 ± 2.9

0.003

54.1 ± 2.0

Resting MBF (mL/min/g)

-

0.85 ± 0.12

-

0.86 ± 0.16

0.150

0.74 ± 0.10

Stress MBF (mL/min/g)

-

1.21 ± 0.18

-

1.37 ± 0.26

0.172

1.81 ± 0.29†

MPR

-

1.44 ± 0.22

-

1.62 ± 0.35

0.023

2.46 ± 0.34†

ECV

-

30.1 ± 0.5

-

28.0 ± 1.6

<0.001

25.3 ± 0.18†

  1. Time between transplantation and scan is given in brackets.
  2. p values refer to the significance of the difference between scans. The significance of the difference between healthy volunteers and scan 4 is denoted by *(p < 0.05) and †(p < 0.01). MBF indicates myocardial blood flow; MPR myocardial perfusion reserve; LGE late gadolinium enhancement; ECV myocardial extracellular volume. Other abbreviations as per Table 2.