Table 3 Characteristics of responders vs non responders – Phase 2

N

35

15

Sex (male/female)

23/12

12/3

0.31

Aetiology

24 DCM

7 DCM

0.14

11 ICM

8 ICM

QRS duration (ms)

149 ± 20

141 ± 23

0.27

QRS morphology (LBBB/RBBB/IVCD)

23/1/11

5/3/7

0.04

Number of patients with scar on CMR n(%)

12 (34)

9 (60)

0.11

Scar burden on CMR (% of myocardium) in those patients with scar

22.2 ± 13.0

29.4 ± 8.4

0.17

Volume change SDI (%)

15.2 ± 6.2

8.5 ± 4.5

<0.001

LV lead position

0.20

Lateral

17

4

Posterolateral

14

8

Anterior

2

3

Posterior

2

0

LV lead in area with >50% transmural scar n (%)

1(3)

7(47)

<0.001