Table 3 Clinical characteristics and CMR-results in patients with and without cardiac fibrosis

Age (years), mean (SD)

51 (18)

44 (10)

0.28

SBP (mmHg), mean (SD)

128 (104–168)

117 (97–135)

0.17

DBP (mmHg), mean (SD)

78 (65–95)

73 (56–101)

0.14

NT-ProBNP (pmol/l), median (range)

9 (1–18)

11 (1–41)

0.38

Myoblobin (ug/l), median (range)

103 (34–162)

69 (27–258)

0.56

CK (U/l), median (range)

199 (56–498)

162 (42–780)

0.61

Handgrip (MRC), median (range)

3.8 (1–5)

4.0 (2–5)

0.68

Ankle dorsal flexion (MRC), median (range)

5 (1–5)

4.5 (3–5)

0.77

CMR-results

LVEF%, median (range)

63 (38–71)

66 (60–80)

0.06

LGE (g), median (range)

4 (1–17)

0

<0.001

LVEF ≤ 50%, n (%)

2 (17)

0

0.15

LVEDV (ml/m²), median (range)

83 (53–130)

71 (57–108)

0.16

LVESV (ml/m²), median (range)

31 (15–73)

25 (13–43)

0.03

LV mass (g/m²), median (range)

55 (43–83)

46 (36–64)

0.02

LA vol. (ml/m²), median (range)

52 (36–87)

46 (35–69)

0.04

ECG

PR interval (ms), median (range)

191 (160–220)

190 (130–260)

0.85

QRS interval (ms), median (range)

96 (70–160)

86 (78–120)

0.43

QTc interval (ms), median (range)

411 (360–516)

407 (346–478)

0.66

AVB grade I

3

7

0.69

LBBB

1

0

0.40

IRBBB

4

0

0.02

Holter-monitoring

AVB grade II

0

3

0.25

AF/AFL

3

1

0.27

SVT

2

0

0.15

NSVT

1

0

0.40

VPC/h, median (range)

3 (0–421)

0 (0–69)

0.30

Echocardiography

LVEF (%), median (range)

57 (45–53)

58 (48–67)

0.34

IVS (mm), median (range)

8 (5–11)

8 (6–13)

0.83

LVEDD (mm), median (range)

50 (40–60)

46 (40–60)

0.24

LVPW (mm), median (range)

8 (5–11)

7 (6–12)

0.77

LV mass (g/m2), median (range)

74 (47–141)

68 (46–87)

0.74

LA vol. (ml/m²), median (range)

26 (17–38)

24 (14–29)

0.08

GLS avg. (%), median (range)

−19 (−14 to −23)

−18 (−14 to −25)

0.75

E/A

1.2 (0.6-2.6)

1.4 (0.8-2.4)

0.69

E/E’ (lateral)

5.4 (3.5-7.4)

4.9 (3.6-8.2)

0.39

MV dec. time (ms)

150 (91–214)

157 (107–239)

0.81