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Table 1 Population characteristics

From: Evaluation of diastolic function by three-dimensional volume tracking of the mitral annulus with cardiovascular magnetic resonance: comparison with tissue Doppler imaging

 

Overall

Normal diastolic function‡ (n = 62)

Diastolic dysfunction‡ (n = 62)

P

Clinical

    

Age, years

51 ± 17

40 ± 14

61 ± 14

<0.001*

Male, n (%)

76

31 (49%)

45 (65%)

0.046*

Heart Rate, bpm

71 ± 12

72 ± 12

71 ± 12

0.628

Cardiovascular risk factors

    

Hypertension, n (%)

54

16 (26%)

38 (61%)

<0.001*

Hyperlipidemia, n (%)

52

17 (27%)

35 (56%)

0.002*

Diabetes mellitus, n (%)

9

3 (5%)

6 (10%)

0.491

Tobacco use, n (%)

45

19 (31%)

26 (42%)

0.262

Coronary artery disease, n (%)

29

7 (11%)

22 (35%)

0.003*

Cardiovascular symptoms

    

Angina, n (%)

32

18 (29%)

14 (23%)

0.539

Dyspnea, n (%)

28

9 (15%)

19 (31%)

0.052†

Palpitation/Arrhythmia, n (%)

29

15 (24%)

14 (23%)

1.000

Syncope/Pre-syncope, n (%)

20

10 (16%)

10 (16%)

1.000

Asymptomatic, n (%)

35

20 (32%)

15 (24%)

0.425

Structural heart disease on CMR

    

Normal, n (%)

57

42 (68%)

15 (24%)

<0.001*

Ischemic heart disease, n (%)

10

3 (5%)

7 (11%)

0.323

Congenital heart disease, n (%)

4

3 (5%)

1 (2%)

0.619

Infiltrative disease, n (%)

5

1 (2%)

4 (6%)

0.365

LV hypertrophy, n (%)

30

6 (10%)

24 (39%)

<0.001*

Dilated cardiomyopathy, n (%)

2

0 (0%)

2 (3%)

0.496

Inflammatory cardiomyopathy, n (%)

9

5 (8%)

4 (6%)

1.000

Function measures by TTE

    

Interventricular septal wall thickness, mm

1.11 ± 0.39

0.96 ± 0.32

1.25 ± 0.41

<0.001*

Inferolateral wall thickness, mm

0.98 ± 0.18

0.9 ± 0.15

1.06 ± 0.17

<0.001*

LV end-diastolic diameter, mm

4.52 ± 0.6

4.69 ± 0.54

4.35 ± 0.61

0.001*

LV end-systolic diameter, mm

2.86 ± 0.52

2.94 ± 0.49

2.78 ± 0.55

0.102

LV mass index, g/m2

87 ± 27

80 ± 21

95 ± 31

0.010*

LV ejection fraction,%

64 ± 6

62 ± 6

65 ± 7

0.059†

LA volume index, ml/m2

25 ± 9

22 ± 7

27 ± 10

0.001*

LA dilatation, n (%)

30

6 (10%)

24 (39%)

<0.001*

Function measures by CMR

    

LV end-diastolic volume, mL

152 ± 39

157 ± 40

147 ± 39

0.211

LV end-systolic volume, mL

59 ± 20

62 ± 19

57 ± 20

0.234

Stroke volume, mL

93 ± 24

95 ± 24

90 ± 24

0.242

Cardiac output, L/min

7.4 ± 8.7

8.5 ± 12

6.2 ± 2

0.241

Cardiac index, L/min/m2

3.3 ± 0.9

3.4 ± 0.9

3.2 ± 0.9

0.101

LV ejection fraction,%

61 ± 6

61 ± 5

62 ± 7

0.720

  1. Data expressed as mean ± SD or frequencies (percentages). LV = Left ventricular; LA = Left atrial.
  2. *P < 0.05, †P < 0.10, ‡Patient classification based on echocardiography reference.
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Journal of Cardiovascular Magnetic Resonance

ISSN: 1532-429X

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