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Table 2 Comparison between transplant-free survivors and non-survivors of biventricular conversion procedure in the BHLHS group

From: Cardiovascular magnetic resonance parameters associated with early transplant-free survival in children with small left hearts following conversion from a univentricular to biventricular circulation

 

Survivors

Non-survivors

P-value

N

16

6

 

Age at CMR (mo)

46 (0–82)

6.5 (0–46)

0.02

Age at conversion (mo)

47 (0–82)

5 (0–46)

0.02

Procedure to increase LV flow

14 (93)

2 (40)

0.01

CMR parameters

   

LV EDV (ml/m2)

62 (28–88)

31 (21–48)

0.001

LV ESV (ml/m2)

23 (9–49)

15 (10–17)

0.02

LV stroke volume (ml/m2)

35 (20–60)

18 (4–32)

0.002

LV ejection fraction (%)

62 (45–79)

58 (20–67)

0.29

RV EDV (ml/m2)

76 (52–132)

97 (66–110)

0.07

RV ESV (ml/m2)

39 (22–82)

40 (31–46)

0.68

RV stroke volume (ml/m2)

38 (17–64)

59 (36–65)

0.02

RV ejection fraction (%)

51 (27–66)

58 (54–66)

0.08

LV-to-RV stroke volume ratio

0.9 (0.5–1.7)

0.3 (0.06–0.7)

<0.001

MV-to-TV inflow ratio

1.0 (0.4–2.0)

0.5 (0.2–0.9)

0.04

LGE pattern consistent with EFE

12 (80)

3 (60)

0.37

Echo parameters

   

LV EDV (ml/m2)

57 (24–78)

31 (20–51)

0.02

LV stroke volume (ml/m2)

28 (12–37)

24 (12–27)

0.04

Mitral valve diameter z-score

-1.9 (-2.8 – -0.5)

-1.8 (-3.2 – -1.3)

0.55

Aortic valve diameter z-score

-2.1 (-3.9 – -1.4)

-1.8 (-2.1 – -1.4)

0.74

LA pressure (mm Hg)

13.5 (5–16)

14 (6–15)

1.0

LV ED pressure (mm Hg)

12 (8–22)

16.5 (12–22)

0.14

Biventricular conversion CPB time (min)

142 (92–260)

182 (122–239)

0.34

Biventricular conversion LOS (days)

19 (7–97)

87.5 (25–150)

0.20

  1. Values are given as median (range) or n (%).
  2. Abbreviations: BHLHS borderline hypoplastic left heart syndrome, CMR cardiovascular magnetic resonance, CPB cardiopulmonary bypass, EDV end-diastolic volume, EFE endocardial fibroelastosis, ESV end-systolic volume, LA left atrial pressure, LGE late gadolinium enhancement, LOS length of stay, LV left ventricle, MV mitral valve, RV right ventricle, TV tricuspid valve.