Table 7 Distribution of dystrophin gene mutation types according to secondary endpoint occurrence
Dystrophin gene mutation type | Total (N = 81) | Secondary endpoint (N = 18) | No endpoint (N = 63) | p-value |
|---|---|---|---|---|
Deletions affecting the amino-terminal domain, n (%) | 11 (14) | 3 (17) | 8 (13) | 1.00 |
Deletions affecting exons 45–49, n (%) | 30 (37) | 7 (39) | 23 (37) | 0.79 |
Deletions affecting exons 50 and/or 51, n (%) | 15 (19) | 2 (11) | 13 (21) | 0.75 |
Duplication, n (%) | 11 (14) | 5 (28) | 6 (10) | 0.13 |
Point mutation, n (%) | 4 (5) | 1 (5) | 3 (5) | 1.00 |
Other, n (%) | 10 (12) | 0 (0) | 10 (16) | 0.06 |