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Table 1 Characteristics of patients

From: Prognostic value of cardiovascular magnetic resonance derived right ventricular function in patients with interstitial lung disease

 

ILD without RVSD n=58

ILD with RVSD n=18

* P- value

Age

70 ± 7

71 ± 4

0.76

Male sex

37 (64%)

16 (89%)

0.043

MRC dyspnea scale

1.9 ± 0.8

2.7 ± 1.1

0.006

BMI, kg/m2

23.8 ± 4.2

22.1 ± 1.9

0.08

Systolic BP, mmHg

131 ± 15

135 ± 19

0.59

Diastolic BP, mmHg

78 ± 9

77 ± 10

0.66

Heart rate, bpm

71 ± 11

70 ± 11

0.35

Blood testing

   

BNP, pg/ml

22.2 (1.7–42.7)

39.9 (18.9-60.9)

0.58

Creatinine, mg/dl

0.82 (0.68–0.96)

0.76 (0.63-0.89)

0.45

KL-6, U/ml

772 (428-1066)

678 (224-1132)

0.83

LDH, IU/l

234 ± 40

211 ± 50

0.62

CRP, mg/dl

0.15 (0.01-0.29)

0.12 (0.01-0.23)

0.66

Pulmonary function test

ILD without RVSD n=14

ILD with RVSD n=56

* P - value

FVC, % predicted

89.4 (73.2-105.6)

85.8 (82.6-89.0)

0.71

FEV1, % predicted

79.7 ± 15.0

86.2 ± 11.9

0.89

DLCO, % predicted

70.7 ± 17.5

68.1 ± 25.8

0.06

  1. Values are presented as mean ± standard deviation (SD) or median (1st quartile and 3rd quartile).
  2. RV dysfunction was defined as RVEF ≤45% evaluated by cine CMR.
  3. *P value represents significance of difference between ILD patient with RVSD and those without.
  4. BMI: body mass index; BNP: brain natriuretic peptide; BP: blood pressure; CRP: C-reactive protein; DLCO: diffusing capacity of the lungs for carbon monoxide; FEV: forced expiratory volume; FVC: forced vital capacity; ILD: interstitial lung disease; LDH: lactic acid dehydrogenase; MRC: Medical Research Council; RVSD: right ventricular systolic dysfunction.