Ref#
|
Imaging Parameters
|
---|
Start time
a
|
Type
|
n-dir
|
b-value (s /mm
2
)
|
Scan duration
b
|
---|
1
|
2:00
|
DTI
|
6
|
1000
|
1:50
|
2
|
3 :50
|
DTI
|
12
|
1000
|
3:56
|
3
|
7:46
|
DTI
|
6
|
1000
|
1:50
|
4
|
9:36
|
DTI
|
12
|
500
|
3:56
|
5
|
13:32
|
DTI
|
6
|
1000
|
1:50
|
6
|
15:22
|
DTI
|
12
|
2000
|
3:56
|
7
|
19 :18
|
DTI
|
6
|
1000
|
1:50
|
8
|
21:08
|
T1W
|
NA
|
NA
|
18:12
|
9
|
39:20
|
DTI
|
6
|
1000
|
1:50
|
10
|
41:10
|
DTI
|
12
|
1500
|
3:56
|
11
|
45:06
|
DTI
|
6
|
1000
|
1:50
|
12
|
46:57
|
T1W
|
NA
|
NA
|
18:12
|
13
|
65:09
|
DTI
|
6
|
1000
|
1:50
|
14
|
66:59
|
DTI
|
12
|
2500
|
3:56
|
15
|
70:55
|
DTI
|
6
|
1000
|
1:50
|
- The first scan was carried out at 2 h and subsequent serial scans were carried out without moving the heart in the scanner. A baseline scan taking 1 h 50 m for 6 diffusion directions at b = 1000 s:mm2 was performed at serial time-points throughout the imaging study to explore any changes in diffusion as a result of time elapsed from killing/perfusion fixation. Interspersed between these baseline scans two T1W FLASH scans were performed at 50 × 50 × 50 μm resolution, as well as a series of diffusion scans with different numbers of directions and different b-values. All diffusion scans were at 200 × 200 × 200 μm resolution. Ref #: reference number for this scan; a– time post-fixation (h:min); bduration (h:min); Type: DTI - diffusion tensor magnetic resonance imaging; T1W is T1-weighted FLASH; FLASH: fast low angle shot; n-dir: number of diffusion directions; NA: not applicable.