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Table 1 Baseline characteristics

From: Comparison of cardiovascular magnetic resonance characteristics and clinical consequences in children and adolescents with isolated left ventricular non-compaction with and without late gadolinium enhancement

  All Children Presence of LGE  
Variable (n = 40) Yes (n = 10) No (n = 30) p Value
Age (years) 13.7 ± 3.3 14.0 ± 2.1 13.6 ± 3.6 0.753
Male, n (%) 29 (73) 9 (90) 20 (67) 0.233
Family history of LVNC, n (%) 3 (8) 1 (10) 2 (7) 1.000
Symptoms     
Dyspnoea, n (%) 21 (53) 9 (90) 12 (40) 0.004
Chest pain, n (%) 2 (5) 0 2 (7) 1.000
Syncope/pre-syncope, n (%) 7 (18) 1 (10) 6 (20) 0.651
Thrombo-embolic events, n (%) 0 0 0  
NYHA functional class 2.4 ± 1.0 3.0 ± 0.9 2.1 ± 0.9 0.016
I, n (%) 10 (25) 1 (9) 9 (30)  
II, n (%) 11 (28) 1 (9) 10 (33)  
III, n (%) 14 (35) 5 (55) 9 (30)  
IV, n (%) 5 (12) 3 (27) 2 (7)  
Abnormal ECG, n (%) 36 (90) 10 (100) 26 (87) 0.559
VT/VF, n (%) 7 (18) 3 (30) 4 (13) 0.361
Medications     
β-Blockers, n (%) 29 (73) 8 (80) 21 (70) 0.694
ACEI/ARB, n (%) 29 (73) 10 (100) 19 (63) 0.020
Aldosterone antagonists, n (%) 27 (68) 10 (100) 17 (57) 0.008
Loop diuretics, n (%) 22 (55) 9 (90) 13 (43) 0.011
Amiodarone, n (%) 2 (5) 2 (20) 0 0.067
  1. Values are mean ± SD or n (%)