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Table 4 AUC for direction and layer of strain versus >50 % transmurality of scar

From: Clinical experience of strain imaging using DENSE for detecting infarcted cardiac segments

Direction and layer of strain

AUC

Sens (%) at spec = 80 %

Strain cut-off value

Scar

Control

p-value

Radial subendocardial strain SA

0.60

27

N/A

4 ± 10

9 ± 11

0.002

Radial epicardial strain SA

0.69

45

N/A

9 ± 13

19 ± 14

<0.001

Radial transmural strain SA

0.66

39

N/A

7 ± 11

14 ± 13

<0.001

Radial transmural radial strain LA

0.67

40

N/A

4 ± 11

12 ± 13

<0.001

Circumferential subendocardial strain

0.94

95

−17

−9 ± 6

−19 ± 3

<0.001

Circumferential epicardial strain

0.92

91

−14

−7 ± 5

−16 ± 4

<0.001

Circumferential transmural strain

0.93

94

−15

−8 ± 5

−17 ± 4

<0.001

Longitudinal transmural strain

0.80

66

−10

−7 ± 7

−12 ± 4

<0.001

  1. Strain for segments with transmurality in excess of 50 % (80 segments) is compared with strain in 356 control segments, regardless of location. AUC is presented together with sensitivity at 80 % specificity and the corresponding cut-off value for strain, when applicable. For strain with AUC less than 0.70, a cut-off value was not calculated, N/A = Not Applicable