From: The diagnostic value of iron oxide nanoparticles for imaging of myocardial inflammation – quo vadis?
Object of study | Field-strength B0 in T | # Animals | Dose in mg Fe/kg | Average particle size in nm | Coating | Half-life in h* | Relaxivites in mM−1 s−1 | |
---|---|---|---|---|---|---|---|---|
Myocardial infarct | Chapon et al. 2003 [50], | 7.0 | 42 | 1, 5, 10 | 50 | Dextran | 0.8 | R1 = 1.2, R2 = 24; (7 T) |
Sosnovik et al. 2007 [51], | 9.4 | 21 | 3, 10, 20 | 32 | Cross-linked dextrans | 10 | ||
Montet-Abou et al. 2009 [52], | 1.5 | 44 | 10 | 15 | Polymer | 6 | ||
Protti et al. 2014 [53], | 7.0 | 73 | 15 | 7 | Citrate | 2 | R1 = 30, R2 = 39; (0,47 T) | |
Myocarditis | Moon et al. 2012 [54], | 4.7 | 90 | 10 | 85 | Silica | 2.8 | R2 = 130; (4,7 T) |