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Table 4 Patient Characteristics, Gadolinium Dose, and Characteristics of Reaction

From: 2015 Update on Acute Adverse Reactions to Gadolinium based Contrast Agents in Cardiovascular MR. Large Multi-National and Multi-Ethnical Population Experience With 37788 Patients From the EuroCMR Registry

 

All

Gadopentetat (Magnevist)

Gadoteracid (Dotarem)

Gadobenat (Multihance)

Gadotbutrol (Gadovist)

Gadoteridol (Prohance)

Gadodiamide (Omniscan)

Other*

All

45

20

5

3

9

2

3

3

Age (years, mean)

51.9

50.8

48.2

68.0

49.6

38.0

62.0

56.0

SD

16.5

18.1

19.0

4.6

16.1

14.1

4.0

13.0

Median

54.0

54.0

53.0

69.0

42.0

38.0

62.0

56.0

Range

16-77

16-74

25-69

63-72

31-77

28-48

58-66

43-69

Sex

        

Male (%)

62.2

75.0

60.0

33.3

44.4

50

66.7

66.7

Contrast dose (ml, mean)

20.6

22.5

24.8

13.7

13.2

14.3

20.0

23.0

SD

8.3

7.5

8.8

3.2

4.3

17.0

8.0

11.5

Median

20.0

22.5

28.0

15.0

14.0

28.0

20.0

27.0

Range

7-40

7-36

10-32

10-16

10-21

16-40

12-28

10-32

Category of reaction

        

Mild

43

18

5

3

9

2

3

3

Moderate

0

0

0

0

0

0

0

0

Severe

2

2

0

0

0

0

0

0

Symptoms

        

Allergic shock

2

2

0

0

0

0

0

0

Cardiac arrest

0

0

0

0

0

0

0

0

Dyspnoea

1

1

0

0

0

0

0

0

Bronchospasm

1

1

0

0

0

0

0

0

Nausea

10

3

0

1

2

0

2

2

Vomiting

6

3

0

0

0

0

2

1

Warmth

3

2

0

1

0

0

0

0

Headache

2

1

0

0

0

0

0

1

Dizziness

5

3

0

0

0

0

2

0

Altered taste

1

0

0

0

0

0

0

1

Itching

9

2

1

1

4

1

0

0

Flushing

10

2

1

1

6

0

0

0

Chills

2

1

0

0

1

0

0

0

Sweats

3

2

0

0

1

0

0

0

Rash/Hives

15

4

4

2

2

2

1

0

Swelling of eye/face

1

1

0

0

0

0

0

0

Anxiety

6

6

0

0

0

0

0

0

Treatment

        

Observation

30

14

3

2

5

1

2

3

Antihistamines

18

4

3

2

4

1

3

1

Steroids

14

3

1

2

3

2

3

0

Adrenaline

2

2

0

0

0

0

0

0

  1. *Dotarem is included in Other