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Table 4 Patient Characteristics, Gadolinium Dose, and Characteristics of Reaction

From: 2015 Update on Acute Adverse Reactions to Gadolinium based Contrast Agents in Cardiovascular MR. Large Multi-National and Multi-Ethnical Population Experience With 37788 Patients From the EuroCMR Registry

  All Gadopentetat (Magnevist) Gadoteracid (Dotarem) Gadobenat (Multihance) Gadotbutrol (Gadovist) Gadoteridol (Prohance) Gadodiamide (Omniscan) Other*
All 45 20 5 3 9 2 3 3
Age (years, mean) 51.9 50.8 48.2 68.0 49.6 38.0 62.0 56.0
SD 16.5 18.1 19.0 4.6 16.1 14.1 4.0 13.0
Median 54.0 54.0 53.0 69.0 42.0 38.0 62.0 56.0
Range 16-77 16-74 25-69 63-72 31-77 28-48 58-66 43-69
Sex         
Male (%) 62.2 75.0 60.0 33.3 44.4 50 66.7 66.7
Contrast dose (ml, mean) 20.6 22.5 24.8 13.7 13.2 14.3 20.0 23.0
SD 8.3 7.5 8.8 3.2 4.3 17.0 8.0 11.5
Median 20.0 22.5 28.0 15.0 14.0 28.0 20.0 27.0
Range 7-40 7-36 10-32 10-16 10-21 16-40 12-28 10-32
Category of reaction         
Mild 43 18 5 3 9 2 3 3
Moderate 0 0 0 0 0 0 0 0
Severe 2 2 0 0 0 0 0 0
Symptoms         
Allergic shock 2 2 0 0 0 0 0 0
Cardiac arrest 0 0 0 0 0 0 0 0
Dyspnoea 1 1 0 0 0 0 0 0
Bronchospasm 1 1 0 0 0 0 0 0
Nausea 10 3 0 1 2 0 2 2
Vomiting 6 3 0 0 0 0 2 1
Warmth 3 2 0 1 0 0 0 0
Headache 2 1 0 0 0 0 0 1
Dizziness 5 3 0 0 0 0 2 0
Altered taste 1 0 0 0 0 0 0 1
Itching 9 2 1 1 4 1 0 0
Flushing 10 2 1 1 6 0 0 0
Chills 2 1 0 0 1 0 0 0
Sweats 3 2 0 0 1 0 0 0
Rash/Hives 15 4 4 2 2 2 1 0
Swelling of eye/face 1 1 0 0 0 0 0 0
Anxiety 6 6 0 0 0 0 0 0
Treatment         
Observation 30 14 3 2 5 1 2 3
Antihistamines 18 4 3 2 4 1 3 1
Steroids 14 3 1 2 3 2 3 0
Adrenaline 2 2 0 0 0 0 0 0
  1. *Dotarem is included in Other