Clinical presentation
| |
Acute chest pain
|
23
|
New-onset (days up to 3 months) or worsening of: dyspnoea at rest or exercise/fatigue, with or without left and/or right heart failure signs
|
16
|
Palpitations/arrhythmia symptoms/syncope/aborted sudden cardiac death
|
18
|
Cardiogenic shock
|
1
|
Diagnostic criteria
| |
ECG/Holter/stress test features
|
31
|
Elevated TnT/TnI
|
26
|
Functional and structural abnormalities on cardiac imaging (echo/angio/CMR)
|
31
|
Tissue characterization by CMR
| |
Visual edema (T2-weighted imaging)
|
23
|
T2-Ratio ≥1.9 [6, 22]
|
25
|
Early Enhancement Ratio (EGEr) >4
|
17
|
Visual LGE of non ischemic pattern
|
30
|
Edema + EGEr positive
|
1
|
Edema + LGE positive
|
9
|
EGEr + LGE positive
|
6
|
3 out of 3 criteria positive
|
15
|
Exclusion of CAD by coronary angiography
|
31
|