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Table 1 Baseline characteristics

From: Cost-minimization analysis of three decision strategies for cardiac revascularization: results of the “suspected CAD” cohort of the european cardiovascular magnetic resonance registry

  Total population Atypical chest pain Typical angina p-values a
Demographics
    n (%) 3’647 (100 %) 1’786 (49.0 %) 582 (16.0 %) -
    Male (%) 58.7 % 45.7 % 42.8 % <0.001
    Age at baseline (y); mean (range) 61.6 (14–92) 61.1 (14–92) 62.6 (26–88) <0.05
    Weight (kg); mean (range) § 80.4 (28–183) 80.2 (30–183) 79.7 (28–182) ns
Risk profile
    Hypertension §     ns
      - none 38.1 % 39.1 % 35.4 %
      - treated 58.1 % 56.7 % 60.3 %
      - untreated 3.9 % 4.3 % 4.3 %
    Dyslipidemia ǁ 42.2 % 40.5 % 45.9 % 0.059
    Diabetes mellitus ǁ 13.3 % 10.8 % 15.0 % <0.001
    Smoker ǁ     ns
      - No 74.5 % 73.9 % 73.9 %
      - Current 12.9 % 12.9 % 13.8 %
      - Previous 12.7 % 13.2 % 12.4 %
    Family history of CAD § 27.0 % 28.3 % 29.4 % <0.05
Reasons for CAD work-up
      - Patient complaints 72.7 % 89.7 % 89.7 % <0.001
      - Presence of cardiovascular risk factors 55.9 % 53.4 % 53.1 % <0.001
      - Ambiguous Stress ECG 20.2 % 17.4 % 14.4 % <0.001
      - Ambiguous Stress Echocardiography 1.9 % 1.4 % 1.2 % <0.01
      - Ambiguous Stress SPECT 0.3 % 0.2 % 0.5 % ns
      - Ambiguous Cardiac CT 0.9 % 0.7 % 0.5 % ns
Treatment: n (%)
    Revascularizations 226 (6.2 %) 81 (4.5 %) 75 (12.9 %) <0.001
    - PCI only 179 (4.9 %) 70 (3.9 %) 53 (9.1 %) <0.001
    - CABG only 41 (1.1 %) 10 (0.6 %) 19 (3.3 %) <0.001
    - PCI and CABG 6 (0.2 %) 1 (0.1 %) 3 (0.5 %) 0.059
Outcome (complications): n (%)
    Primary endpoint 75 (2.1 %) 33 (1.9 %) 11 (1.9 %) ns
    - Mortality : all cause 34 (0.9 %) 15 (0.8 %) 7 (1.2 %) ns
    - Cardiac death 7 (0.2 %) 6 (0.4 %) 0 (0.0 %) ns
    - Cardiac death and unknown cause 23 (0.6 %) 13 (0.7 %) 2 (0.3 %) ns
    - Non-fatal myocardial infarction 11 (0.3 %) 5 (0.2 %) 2 (0.3 %) ns
    - Aborted sudden cardiac death 8 (0.3 %) 4 (0.2 %) 1 (0.2 %) ns
    - Stroke 18 (0.5 %) 10 (0.6 %) 1 (0.2 %) ns
  1. a Differences for age and weight were assessed by one-way ANOVA and for the other parameters by the Chi-square statistic. P-values >0.10 are reported as ns. Reasons for CAD work-up may add up to >100 % as several reasons per patient may apply. n = 3’643; n = 3’646; § n = 3’642; ǁ n = 3’641