Fig. 1

Validation of T1 and ECV mapping software. To confirm that our results were quantitatively correct, we generated a simulated dataset for both pre and post-contrast data. In this dataset, we use inversion times of 120, 1018, 1698, 3125 milliseconds and 280, 693, 755, 1860 milliseconds for pre and post-contrast data respectively. A hematocrit value of 0.45 was used. Three different pseudo regions of interest (ROIs) were generated to simulate the blood pool and two left ventricular ROIs. This simulated data is generated such that we expect the following T1 times for the following regions: T1pre_bloodpool = 1498.3 ms, T1pre_LV1 = 1054.7 ms and T1pre_LV2 = 1393.6 ms, T1post_bloodpool = 419.7 ms, T1post_LV1 = 529.7 ms, and T1post_LV2 = 419.7 ms. We also expect ECV values for the following regions to be 0.55, 0.33, and 0.60 respectively. The results in (a), (b), and (c) match with the a priori defined dataset