| |
HF patients with low LVEF
|
HF patients with normal LVEF
|
Control subjects
|
p value
|
|---|
|
(n = 25)
|
(n = 23)
|
(n = 21)
|
|---|
|
Clinical profile
| | | | |
|
Male sex, n (%)
|
21 (84 %)
|
22 (96 %)
|
17 (81 %)
|
0.31
|
|
Age (years)
|
56.0 ± 7.7
|
56.1 ± 8.7
|
58.9 ± 7.2
|
0.39
|
|
Height (cm)
|
166.8 ± 8.6
|
165.8 ± 7.0
|
164.3 ± 5.0
|
0.48
|
|
Weight (kg)
|
71.6 ± 15.9
|
72.5 ± 12.0
|
70.9 ± 10.4
|
0.92
|
|
BMI (kg/m2)
|
25.5 ± 4.3
|
26.4 ± 4.1
|
26.3 ± 4.0
|
0.75
|
|
SBP (mmHg)
|
127.0 ± 25.4*
|
134.0 ± 18.6
|
145.7 ± 7.0
|
0.03
|
|
DBP (mmHg)
|
74.3 ± 10.8*
|
73.7 ± 9.4 *
|
83.7 ± 12.5
|
0.01
|
|
Biochemical profile
| | | |
|
Triglyceride (mg/dL)
|
150.4 ± 60.3
|
168.5 ± 98.2
|
179.1 ± 4.8
|
0.65
|
|
Total cholesterol (mg/dL)
|
189.8 ± 34.3
|
180.6 ± 31.7
|
178.4 ± 0.0
|
0.70
|
|
LDL (mg/dL)
|
115.5 ± 35
|
108.2 ± 29.7
|
95.1 ± 50.2
|
0.39
|
|
VLDL (mg/dL)
|
29.7 ± 12.6
|
33.8 ± 19.6
|
31.3 ± 23.3
|
0.74
|
|
HDL (mg/dL)
|
45.4 ± 10.1
|
38.6 ± 8.4
|
45.9 ± 25.6
|
0.14
|
|
T-cho/HDL
|
4.4 ± 1.3
|
4.9 ± 1.3 *
|
3.2 ± 2.0
|
0.04
|
|
LDL/HDL
|
2.7 ± 1.1
|
2.9 ± 1.1
|
3.3 ± 3.7
|
0.74
|
|
Non-HDL (mg/dL)
|
144.4 ± 37.3
|
142.0 ± 30.3
|
116.2 ± 3.9
|
0.27
|
|
Fasting glucose (mg/dL)
|
121.2 ± 38.1
|
113.4 ± 77.1
|
93 ± 41.3
|
0.52
|
|
HbA1c (mg/dL)
|
6.4 ± 1.2
|
6.5 ± 1.5 *
|
4.1 ± 2.7
|
0.03
|
- Data are expressed as means ± standard deviations. P values are calculated from one-way analysis of variance
-
Abbreviations: HF, heart failure; LVEF left ventricular ejection fraction, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, DM diabetes mellitus, MI prior myocardial infarction, DCM dilated cardiomyopathy, HDL high-density lipoprotein cholesterol, T-cho total cholesterol VLDL very low-density lipoprotein cholesterol, LVL low-density lipoprotein cholesterol, HbA1c glycated hemoglobin
-
*
p < 0.05 vs. controls
