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Table 4 Analysis of the modified remodeling index, vessel dimensions, AHA-LT distribution, and plaque-components of internal carotid arteries (ICA) with and without significant luminal stenosis (>50 %)

From: Expansive arterial remodeling of the carotid arteries and its effect on atherosclerotic plaque composition and vulnerability: an in-vivo black-blood 3T CMR study in symptomatic stroke patients

Vessel dimensions mean

Stenotic ICA (>50 %) (n = 44)

Non-stenotic ICA (n = 158)

p-value

Modifed remodeling index

2.22 ± 0.82

2.21 ± 0.83

n.s.

Lumen area [mm2]

13.7 ± 5.50

23.0 ± 9.2

<0.0001

Wall area [mm2]

32.1 ± 14.0

27.9 ± 10.9

0.0371

Outher wall area [mm2]

45.8 ± 16.3

50.9 ± 17.1

n.s.

Normalized wall index

0.69 ± 0.09

0.55 ± 0.08

<0.0001

Wall thickness [mm]

2.1 ± 0.60

1.6 ± 0.4

<0.0001

AHA lesion type distribution

   

AHA LT I (%; x/n)

0.0 % (0/44)

29.8 % (47/158)

<0.0001

AHA LT III (%; x/n)

18.2 % (8/44)

26.0 % (41/158)

n.s.

AHA LT IV/V (%; x/n)

38.6 % (17/44)

13.9 % (22/158)

0.001

AHA LT VI (%; x/n)

25.0 % (11/44)

8.2 % (13/158)

0.006

AHA LT VII (%; x/n)

18.2 % (8/44)

22.2 % (35/138)

n.s.

Plaque components

   

Intraplaque hemorrhage (%; x/n)

25.0 % (11/44)

7.6 % (12/158)

0.0029

Lipidrich necrotic core (%; x/n)

63.6 % (28/44)

21.5 % (34/158)

<0.0001

Calcification (%; x/n)

50.0 % (22/44)

27.2 % (43/158)

0.0060

Ulceration (%; x/n)

9.1 % (4/44)

1.9 % (3/158)

0.0417

Thrombus (%; x/n)

2.3 % (1/44)

0.6 % (1/158)

n.s.