Regional myocardial microvascular dysfunction in cardiac amyloid light-chain amyloidosis: assessment with 3T cardiovascular magnetic resonance

Table 5 ROC analysis of first-pass perfusion for detecting microvascular dysfunction between AL-CA patients with preserved systolic function and normal controls

	Cutoff	AUC	Sensitivity (%) (95 % CI)	Specificity (%) (95 % CI)
Basal segment
Upslope	5	0.888	87 (82–93)	81 (74–87)
TTM	20.8	0.843	79 (70–85)	73 (66–80)
MaxSI	42	0.816	68 (59–76)	85 (78–90)
Mid-ventricular segment
Upslope	4	0.794	58 (49–67)	90 (84–94)
TTM	19.9	0.848	85 (78–91)	67 (59–75)
MaxSI	42	0.741	58 (49–67)	82 (75–88)
Apical segment
Upslope	4	0.747	52 (41–63)	94(87–98)
TTM	21.87	0.795	77 (67–86)	70 (60–79)
MaxSI	41	0.610	37 (27–48)	86 (78–92)

Notes: AUC = area under the ROC curve. The abbreviations are the same as in Tables 1 and 2

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